Accuracy and reproducibility of the assessment of the global ejection fraction using 195mAu and a single-crystal digital gamma camera: Influence of collimator design
Creators
- 1. Milan Univ. (Italy). Nuclear Medicine Dept.
- 2. Milan Univ. (Italy). Ist. di Scienze Mediche Bassini
- 3. Ciba Foundation, Milan (Italy)
Description
A sequence of RAO first-pass studies (first with 99mTc and then twice with 195mAu) was performed in 18 normal volunteers and in 12 CAD patients using two different types of collimator for medium energy: a standard collimator (MEMS) and a special high-sensitivity collimator (MEHS). The following data were compared: the peak count rate, the net LV end-diastolic counts and the LVEF. Using MEMS the end-diastolic counts acquired were so low (12% of 99mTc average value) that EF standard deviation had a mean value of 0.061 (range 0.045-0.081). With MEHS the following results were obtained: 1. the peak count rate and LV net end-diastolic counts with 195mAu were 55% and 50% respectively, of 99mTc values; 2. a good correlation was shown between LVEF values either with 99mTc and 195mAu (r = .97), or with 195mAu sequential studies (r = .98). (orig.)
Abstract (German)
Erste-Passage-Untersuchungen in RAO (zunaechst mit 99mTc, dann zweimal mit 195mAu wurden bei 18 Gesunden und bei 12 Patienten mit koronarer Herzkrankheit durchgefuehrt. Hierbei wurden zwei unterschiedliche Mittelenergie-Kollimatoren eingesetzt: ein Standard-Kollimator (MEMS) und ein spezieller hochempfindlicher Kollimator (MEHS). Folgende Daten wurden verglichen: die maximale Zaehlrate, die linksventrikulaere enddiastolische Zaehlrate (netto) und die linkesventrikulaere Auswurffraktion. Mit MEMS waren die enddiastolischen Zaehlraten so niedrig (12% des Technetium-Wertes), dass die Streubreite der Auswurffraktion einen Mittelwert von 0,061 (Streubereich 0.045-0.081) aufwies. Fuer den MEHS betrugen maximale Zaehlrate bzw. linksventrikulaere enddiastolische Zaehlrate mit 195mAu 55% bzw. 50% der Technetium-Werte. Fuer die Werte der Auswurffraktion ergab sich eine gute Korrelation (99mTc vs 195mAu: r = 0.97). Die 195mAu-Werte waren exzellent reproduzierbar (r = 0.98). (orig.)Additional details
Publishing Information
- Journal Title
- Nuklearmedizin
- Journal Volume
- 26
- Journal Issue
- 4
- Series
- Nuklearmedizin.
- Journal Page Range
- 309-313
- ISSN
- 0029-5566
- CODEN
- NUKLD
INIS
- Country of Publication
- Germany
- Country of Input or Organization
- Germany
- INIS RN
- 19028141
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- ACCURACY; CARDIOVASCULAR DISEASES; COLLIMATORS; COMPARATIVE EVALUATIONS; CORONARIES; DIAGNOSIS; DIGITAL SYSTEMS; GAMMA CAMERAS; GOLD 195; HEART; ISOMERIC NUCLEI; MAN; PATIENTS; RADIOCARDIOGRAPHY; STATISTICS; TECHNETIUM 99
- Descriptors DEC
- ANIMALS; ARTERIES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BLOOD VESSELS; BODY; CAMERAS; CARDIOGRAPHY; CARDIOVASCULAR SYSTEM; DAYS LIVING RADIOISOTOPES; DIAGNOSTIC TECHNIQUES; DISEASES; ELECTRON CAPTURE RADIOISOTOPES; EVALUATION; GOLD ISOTOPES; HEAVY NUCLEI; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MATHEMATICS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; PRIMATES; RADIOISOTOPES; SECONDS LIVING RADIOISOTOPES; TECHNETIUM ISOTOPES; VERTEBRATES; YEARS LIVING RADIOISOTOPES