Published March 1979
| Version v1
Journal article
Nuclear protein and DNA content of cardiomyocytes the irradiated heart being adapted to increased hemodynamic load
Creators
- 1. Tsentral'nyj Nauchno-Issledovatel'skij Rentgeno-Radiologicheskij Inst., Leningrad (USSR)
Description
Enlargement of cardyomyocyte nuclei of rats after local γ-irradiation (2400 R) and with the compensatory hypertrophy is associated with the accumulation of nuclear proteins (non-histone fractions being predominant). Number of polyploid decreases and that of small nuclei, having a reduced content of DNA and protein (and excess histones), increases after irradiation. A combined exposure to radiation and hemodynamic load enhances the observed radiation effects and reduces nuclear changes typical of hypertrophy development
Additional details
Additional titles
- Original title (Russian)
- Содержание ядерных белков и DNK в миоцитах м.иокарда при адаптации облученного сердца к повышенной гемодинамической нагрузке
Publishing Information
- Journal Title
- Radiobiologiya
- Journal Volume
- 19
- Journal Issue
- 2
- Series
- Radiobiologiya.
- Journal Page Range
- 177-183
- ISSN
- 0033-8192
INIS
- Country of Publication
- Russian Federation
- Country of Input or Organization
- USSR
- INIS RN
- 11508233
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- ANIMAL CELLS; AORTA; BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL REPAIR; CELL NUCLEI; CORRELATIONS; DNA; EXPERIMENTAL DATA; GAMMA RADIATION; GRAPHS; HYPERTROPHY; LOCAL IRRADIATION; MYOCARDIUM; PROTEINS; RATS; SURGERY; TIME DEPENDENCE
- Descriptors DEC
- ANIMALS; ARTERIES; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; BLOOD VESSELS; BODY; CARDIOVASCULAR SYSTEM; CELL CONSTITUENTS; DATA; DATA FORMS; DISEASES; ELECTROMAGNETIC RADIATION; HEART; INFORMATION; IONIZING RADIATIONS; IRRADIATION; MAMMALS; MEDICINE; MUSCLES; NUCLEIC ACIDS; NUMERICAL DATA; ORGANIC COMPOUNDS; ORGANS; PATHOLOGICAL CHANGES; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES
Optional Information
- Notes
- For English translation see the journal Radiobiology (USA).