Influence of head X-irradiation on neuroendocrine functions in thymectomized male rats
Description
The present study showed that the functions of the hypothalamic-pituitary-gonadal and hypothalamic-adrenocortical systems changed in adult male rats thymectomized within 48 h after their birth. Two days later, head irradiation with 10 Gy x-rays was performed in the thymectomized male rats, serum LH and FSH, serum and urine testosterone and corticosterone, pituitary and testicular cAMP and hypothalamic β-EP and L-Enk contents were all reduced in different degrees, except the hypothalamic M-Enk content was increased, indicating that the changes were not in the same direction as those in intact male rats after head irradiation. These results suggest that the changes in head irradiated thymectomized male rats may differ from the changes seen in head irradiated intact male rats because of the influence of thymectomy on the neuroendocrine functions
Additional details
Publishing Information
- Journal Title
- Journal of Norman Bethune University of Medical Sciences
- Journal Volume
- 17
- Journal Issue
- 5
- Journal Page Range
- p. 5-7.
- ISSN
- 0253-3707
- CODEN
- PEIPDB
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 24037929
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL FUNCTIONS; BIOLOGICAL RADIATION EFFECTS; BRAIN; ENDOCRINE GLANDS; HEAD; LOCAL IRRADIATION; RATS; THYMUS; X RADIATION
- Descriptors DEC
- ANIMALS; BIOLOGICAL EFFECTS; BODY; BODY AREAS; CENTRAL NERVOUS SYSTEM; ELECTROMAGNETIC RADIATION; GLANDS; IONIZING RADIATIONS; IRRADIATION; LYMPHATIC SYSTEM; MAMMALS; NERVOUS SYSTEM; ORGANS; RADIATION EFFECTS; RADIATIONS; RODENTS; VERTEBRATES