Published 1989
| Version v1
Journal article
Gestational changes of GABA levels and GABA binding in the human uterus
Description
The concentrations of gamma-aminobutyric acid (GABA), the activities of L-glutamate decarboxylase and GABA-transaminase, and the nature of the sodium-independent binding of GABA were examined in uterine tissue pieces obtained surgically from pregnant and non-pregnant women. GABA concentrations were reduced, while the activity of GABA-transaminase and the specific binding of [3H]GABA significantly increased in specimens from pregnant subjects. These findings suggest some gestation-related functional role for the GABA system in the human uterus
Additional details
Publishing Information
- Journal Title
- Life Sciences
- Journal Volume
- 44
- Journal Issue
- 26
- Series
- Life Sci.
- Journal Page Range
- 2009-2014
- ISSN
- 0024-3205
- CODEN
- LIFSA
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 21002485
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Descriptors DEI
- AMINOBUTYRIC ACID; AMINOTRANSFERASES; BIOCHEMICAL REACTION KINETICS; BIOLOGICAL FUNCTIONS; DECARBOXYLASES; ENZYME ACTIVITY; MAN; TRACER TECHNIQUES; TRITIUM COMPOUNDS; UTERUS
- Descriptors DEC
- AMINO ACIDS; ANIMALS; AUTONOMIC NERVOUS SYSTEM AGENT; BODY; CARBON-CARBON LYASES; CARBOXYLIC ACIDS; DRUGS; ENZYMES; FEMALE GENITALS; HYDROGEN COMPOUNDS; ISOTOPE APPLICATIONS; KINETICS; LYASES; MAMMALS; NEUROREGULATORS; NITROGEN TRANSFERASES; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANS; PRIMATES; REACTION KINETICS; TRANSFERASES; VERTEBRATES