Published 1988 | Version v1
Miscellaneous Metadata-only

Radioimmobilization of biocomponents

Creators

  • 1. Instituto de Pesquisas Energeticas e Nucleares, Sao Paulo (Brazil)

Description

A number of different methodologies are available using radiation processing for the immobilization of biomolecules such as enzymes, antibodies, drugs and transport proteins such as haemoglobin. A simple method which is currently used is the physical immobilization by entrapment in polymer matrix produced by radiation polymerization of a mixture of monomer and bioactive material. Compared with other techniques for immobilization, the radiation polymerization method for the preparation of a matrix is facile and the products have showed good activity and stability (E.G.)

Abstract (Portuguese)

Um grande numero de metodologias sao disponiveis usando processos de radiacao para a imobilizacao de biomoleculas tais como enzimas, anticorpos, antigenes, drogas e transporte de proteinas tais como hemoglobina. Um metodo simples que e comumente usado e o de imobilizacao fisica em matrizes de polimeros por radiacao de polimerizacao de uma mistura de monomeros e material bioativo. Comparada com outras tecnicas para imobilizacao, o metodo de radiacao de polimerizacao para a preparacao de matriz e facil e os produtos tem mostrado boa atividade e estabilidade. (E.G.)

Additional details

Publishing Information

Imprint Title
Proceedings of the 6. Japan Brazil Symposium on Science and Technology
Imprint Pagination
466 p.
Journal Page Range
p. 38-46.
Report number
ACIESP--60(v.4)

Conference

Title
6. Japan-Brazil Symposium on Science and Technology.
Dates
10-12 Aug 1988.
Place
. Sao Paulo, SP (Brazil).

INIS

Country of Publication
Brazil
Country of Input or Organization
Brazil
INIS RN
19103934
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Resource subtype / Literary indicator
Conference
Descriptors DEI
CELLULASE; COBALT 60; ELECTRON BEAMS; ENCAPSULATION; ENZYME ACTIVITY; GAMMA RADIATION; IMMOBILIZATION; IRRADIATION; MONOMERS; UREASE
Descriptors DEC
AMIDASES; BEAMS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; COBALT ISOTOPES; ELECTROMAGNETIC RADIATION; ENZYMES; HYDROLASES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LEPTON BEAMS; MINUTES LIVING RADIOISOTOPES; NON-PEPTIDE C-N HYDROLASES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; PARTICLE BEAMS; RADIATIONS; RADIOISOTOPES; YEARS LIVING RADIOISOTOPES