Results of simulating of post-irradiation kinetics of blood formation
Creators
Description
Hemopoiesis as a sufficiently simple autonomous mechanism is presented, the main organization units and leading regulatory relations are singled out in it. The model demonstrates characteristic reactions known from experimental and clinical material and also forecasts them. By means of simulation it proved possible to detect the phenomenon of blood formation autoactivation, which is based practically on the same principles as artificial activation. Using the simulation one can explain the paradoxical fact of early start of hemopoiesis final repair with the dose growth. The conducted detailed analysis of hemopoiesis system has reduced dynamic notions to the level when the process of hemotology concrete problem solution proved to be duly equipped both methodologically and theoretically
Additional details
Additional titles
- Original title (Russian)
- Итоги математического моделирования пострадиационной динамики гемопоэза
Publishing Information
- Publisher
- Moskovskij universitet.
- Imprint Place
- Moscow (USSR)
- Imprint Title
- Radiation injuries
- Journal Page Range
- p. 148-154.
INIS
- Country of Publication
- USSR
- Country of Input or Organization
- USSR
- INIS RN
- 19095294
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; BIOLOGICAL REGENERATION; BLOOD FORMATION; IONIZING RADIATIONS; MATHEMATICAL MODELS; SIMULATION; STEM CELLS
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL EFFECTS; BIOLOGICAL RECOVERY; RADIATION EFFECTS; RADIATIONS; SOMATIC CELLS
Optional Information
- Notes
- 5 refs,; 1 fig. Imprint:Luchevoe porazhenie.;Ostroe luchevoe porazhenie, poluchennoe v ehksperimente.