Published 1999
| Version v1
Report
Study of the cell cycle control for human malignant mesothelioma lines. Interferon and radiations effect
Description
In order to better understand the inhibition mechanisms of the IFN-R-HU on tumoral development, the IFN-R-U effect on MM lines has been studied. Three groups of lines has been distinguished: eight sensitive lines, two intermediate and three resistant. The sensitive lines showed a triple locking of the cell cycle: in phases S, G1 and G2. The study of the cell cycle control points function, realized by the MM lines radiation exposure showed the points function on G1/S and-or on G2/M and the dependence or non dependence of the cycle stop of the protein P53 and P21 W at F1/CIP1. (A.L.B.)
Availability note (English)
Available from Universite Paris-Val-de-Marne, Paris-12, 61 avenue du General-de-Gaulle 94010 Creteil Cedex (France)Additional details
Additional titles
- Original title (French)
- Etude de la regulation du cycle cellulaire de lignees de mesotheliome malin humain. Effet de l'interferon et des radiations
Publishing Information
- Imprint Pagination
- 41 p.
- Report number
- FRNC-TH--5111
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 34016103
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Thesis, Non-conventional Literature
- Descriptors DEI
- CELL CYCLE; DRUGS; ENZYME INHIBITORS; GAMMA RADIATION; GENES; IMMUNOTHERAPY; INTERFERON; NEOPLASMS; PHARMACOLOGY
- Descriptors DEC
- DISEASES; ELECTROMAGNETIC RADIATION; GROWTH FACTORS; IONIZING RADIATIONS; LYMPHOKINES; MEDICINE; MITOGENS; ORGANIC COMPOUNDS; PROTEINS; RADIATIONS; THERAPY