Published June 1990
| Version v1
Journal article
An early clinical study of Z-100 in leukopenia caused by radiotherapy
- 1. Keio Univ., Tokyo (Japan). School of Medicine
Description
The clinical efficacy of Z-100 for the treatment of leukopenia caused by radiotherapy for malignant tumors was evaluated in an early clinical study using three doses, 2, 10 and 20 μg. According to the evaluation by investigators and time-course of WBC, the highest effective rate was achieved by 20 μg. Adverse reactions occurred in all groups, but there were no serious or clinically relevant reactions. These results suggested that Z-100 is clinically useful for the treatment of leukopenia caused by radiotherapy. (author)
Additional details
Publishing Information
- Journal Title
- Rinsho Hoshasen
- Journal Volume
- 35
- Journal Issue
- 6
- Series
- Rinsho Hoshasen.
- Journal Page Range
- 709-714
- ISSN
- 0009-9252
- CODEN
- RHOSA
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 21086530
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BACILLUS; CARCINOMAS; LEUKOCYTES; LEUKOPENIA; LUNGS; MAMMARY GLANDS; PATIENTS; RADIATION PROTECTION; RADIOPROTECTIVE SUBSTANCES; RADIOTHERAPY; SIDE EFFECTS; UTERUS
- Descriptors DEC
- BACTERIA; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; DISEASES; DRUGS; FEMALE GENITALS; GLANDS; HEMIC DISEASES; MATERIALS; MEDICINE; MICROORGANISMS; NEOPLASMS; ORGANS; PATHOLOGICAL CHANGES; RESPIRATORY SYSTEM; RESPONSE MODIFYING FACTORS; SYMPTOMS; THERAPY