Changes of porous poly(ε-caprolactone) bone grafts resulted from e-beam sterilization process
- 1. Department of Polymer Engineering, Budapest University of Technology and Economics, H-1111 Budapest, Muegyetem Rakpart 3 (Hungary) and Research Center for Biomechanics, Budapest University of Technology and Economics, H-1111 Budapest, Muegyetem Rakpart 3 (Hungary)
- 2. Institute of Applied Radiation Chemistry, Technical University of Lodz, 93-590 Lodz, Wroblewskiego 15 (Poland)
- 3. Department of Polymer Engineering, Budapest University of Technology and Economics, H-1111 Budapest, Muegyetem Rakpart 3 (Hungary)
- 4. Research Center for Biomechanics, Budapest University of Technology and Economics, H-1111 Budapest, Muegyetem Rakpart 3 (Hungary)
Description
The most important mechanical feature of poly(ε-caprolactone) (PCL) foams applied in bone tissue engineering as a scaffold, has been investigated as a function of irradiation dose. Radiation is proposed for the sterilization of the polymer before the implantation. Polycaprolactone scaffold foams were obtained by combination of compression molding and particulate leaching techniques. The porogen was changed in the range 74-96 w% and the irradiation dose was varied from 25 to 150 kGy. Our results show that yield strength is not a function of radiation dose, but is rather influenced by the porosity, while the critical strain is mainly dependent on the dose. All these together mean that the modulus of the elasticity of PCL foams is dependent on both the porosity and the dose
Additional details
Identifiers
- DOI
- 10.1016/j.radphyschem.2007.02.046;
- PII
- S0969-806X(07)00083-7;
Publishing Information
- Journal Title
- Radiation Physics and Chemistry (1993)
- Journal Volume
- 76
- Journal Issue
- 8-9
- Journal Page Range
- p. 1430-1434
- ISSN
- 0969-806X
- CODEN
- RPCHDM
Conference
- Title
- 11. Tihany symposium on radiation chemistry
- Dates
- 26-31 Aug 2006
- Place
- Eger (Hungary)
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- International Atomic Energy Agency (IAEA)
- INIS RN
- 38104026
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- COMPRESSION; ELASTICITY; ELECTRON BEAMS; GRAFT POLYMERS; LACTONES; LEACHING; POROSITY; POROUS MATERIALS; RADIATION DOSES; STERILIZATION
- Descriptors DEC
- BEAMS; DISSOLUTION; DOSES; ESTERS; HETEROCYCLIC COMPOUNDS; LEPTON BEAMS; MATERIALS; MECHANICAL PROPERTIES; ORGANIC COMPOUNDS; ORGANIC POLYMERS; PARTICLE BEAMS; POLYMERS; SEPARATION PROCESSES
Optional Information
- Copyright
- Copyright (c) 2007 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.