Published 1989
| Version v1
Book
Phase 1 study of monoclonal antibody I-131 3F8 targeted radiation therapy of human neuroblastoma
Creators
Description
This study is phase I of monoclonal antibody 131-I 3F8 targeted radiotherapy of human neuroblastoma. A murine IgG3 monoclonal antibody specific for ganglioside GD2(3F8), has unusually high (0.08% ID/g) tumor localization in patients and restricted distribution in normal tissues. Nine patients with refractory neuroblastoma (seven with soft tissue masses, four with bone disease, and three with bone marrow disease) have been treated with intravenous I-131 3F8 (10 μg 3F8) and oral saturated solution of potassium iodide and potassium perchlorate. Results are presented
Additional details
Publishing Information
- Publisher
- Radiological Society of North America Inc.
- Imprint Place
- Oak Brook, IL (USA)
- Imprint Title
- Proceedings of the 75th anniversary scientific assembly and annual meeting of the Radiological Society of North America (Abstracts)
- Imprint Pagination
- 654 p.
- Journal Page Range
- p. 420.
Conference
- Title
- 75. anniversary scientific assembly and annual meeting of the Radiological Society of North America.
- Dates
- 26 Nov - 1 Dec 1989.
- Place
- Chicago, IL (USA).
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 21087416
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE; S60: APPLIED LIFE SCIENCES;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BONE MARROW; GANGLIOSIDES; IMMUNE REACTIONS; IMMUNOTHERAPY; IODINE 131; MONOCLONAL ANTIBODIES; NEOPLASMS; NERVE CELLS; NEUROLOGY; RADIATION DOSES; RADIOTHERAPY; USES
- Descriptors DEC
- ANIMAL CELLS; ANTIBODIES; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; CARBOHYDRATES; DAYS LIVING RADIOISOTOPES; DISEASES; HEMATOPOIETIC SYSTEM; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPES; LIPIDS; MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; RADIOISOTOPES; SACCHARIDES; SOMATIC CELLS; THERAPY; TISSUES
Optional Information
- Secondary number(s)
- CONF-8911163--.