Radionuclide techniques in clinical investigation

A monograph has been written describing the principles underlying the radionuclide tracer methods used to investigate clinical conditions. The introductory chapters include information on the production of safe and efficacious radionuclides, their biological radiation effects and their method of detection by various counting techniques. The remaining chapters deal with the many applications of radionuclide tracer techniques including 1) the measurement of the volume of distribution or the mass of a substance within the body, 2) the measurement of radionuclide absorption, clearance and organ uptake, 3) the measurement of blood flow, 4) simulation of physiological systems and 5) radioimmunoassay and related techniques. The Appendix lists 42 radionuclides with information on their radioactive properties, their production method and their clinical use. (U.K.)