Correlative study on anemia and radiotherapy effects in nasopharyngeal carcinoma
Creators
- 1. Chaozhou Central Hospital, Chaozhou (China). Dept. of Otorhinolaryngology
Description
Objective: To study the effect of oxygen-carrying ability of blood efficacy of radiotherapy for patients with nasopharyngeal carcinoma. Methods: Altogether 161 cases of patients with nasopharyngeal carcinoma were classified according to severity of anemia, and Hb, RBC, MCH, HCT, MCV, MCHC and RDW were tested before, during and after radiotherapy. The patients were followed-up for up to 5 years, the relationship and mechanism among anemia, radiotherapy effects and survival rate was discussed. Results: The survival rate between anemia group and non-anemia group was different significantly (P<0.05). Anemia before radiotherapy, anemia appearance or anemia deterioration during radiotherapy were sensitive factors affecting radiotherapy results. The anemia more severe, the radiotherapy worse. Conclusion: Anemia-hypohemoglobinemia leads to decrease of oxygen-carrying capacity of blood, resulting in oxygen deficiency of tumor cells and their radiotherapy resistance. Therefore this method is worthy of further studies
Additional details
Publishing Information
- Journal Title
- Chinese Journal of Radiological Medicine and Protection
- Journal Volume
- 23
- Journal Issue
- 4
- Journal Page Range
- p. 265-267
- ISSN
- 0254-5098
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 36021298
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- ANEMIAS; BLOOD COUNT; CARCINOMAS; COBALT 60; DYNAMIC FUNCTION STUDIES; EFFICIENCY; ERYTHROCYTES; EXPERIMENTAL DATA; EXTERNAL IRRADIATION; GAMMA RADIATION; HEMOGLOBIN; OXYGEN; PHARYNX; RADIATION DOSES; RADIOSENSITIVITY; RADIOTHERAPY; STATISTICS; SURVIVAL CURVES
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY FLUIDS; CARBOXYLIC ACIDS; COBALT ISOTOPES; DATA; DIGESTIVE SYSTEM; DISEASES; DOSES; ELECTROMAGNETIC RADIATION; ELEMENTS; GLOBINS; HEMIC DISEASES; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; INFORMATION; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IONIZING RADIATIONS; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MATERIALS; MATHEMATICS; MEDICINE; MINUTES LIVING RADIOISOTOPES; NEOPLASMS; NONMETALS; NUCLEAR MEDICINE; NUCLEI; NUMERICAL DATA; ODD-ODD NUCLEI; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PIGMENTS; PORPHYRINS; PROTEINS; RADIATIONS; RADIOISOTOPES; RADIOLOGY; RESPIRATORY SYSTEM; SYMPTOMS; THERAPY; YEARS LIVING RADIOISOTOPES