Published 1978 | Version v1
Journal article Metadata-only

RBE/absorbed dose relationship of d(50)-Be neutrons determined for early intestinal tolerance in mice

Creators

  • 1. Louvain Univ. (Belgium). Centre des Tumeurs

Description

RBE/absorbed dose relationship of d(50)-Be neutrons (ref.: 60Co) was determined using intestinal tolerance in mice (LD50) after single and fractionated irradiation. RBE is 1.8 for a single fraction (about 1000 rad 60Co dose); it increases when decreasing dose and reaches the plateau value of 2.8 for a 60Co dose of about 200 rad. This RBE value is used for the clinical applications with the cyclotron 'Cyclone' at Louvain-la-Neuve

Abstract (French)

La relation EBR/dose absorbee pour les neutrons d(50)-Be (ref. 60Co) a ete determinee pour la tolerance de la muqueuse intestinale chez la souris (DL50) apres irradiations simples et fractionnees. L'EBR est de 1,8 pour 1 fraction (environ 1000 rad 60Co); l'EBR augmente quand la dose decroit et atteint la valeur limite de 2,8 pour les doses 60Co d'environ 200 rad. Cette valeur d'EBR est utilisee pour les applications cliniques effectuees avec le cyclotron Cyclone de Louvain-la-Neuve

Additional details

Additional titles

Original title (French)
Relation EBR/dose absorbee des neutrons d(50)-Be determinee pour la tolerance precoce de la muqueuse intestinale de la souris

Publishing Information

Journal Title
C. R. Seances Soc. Biol. Fil.
Journal Volume
172
Journal Issue
4
Series
C. R. Seances Soc. Biol. Fil.
Journal Page Range
787-790

INIS

Country of Publication
France
Country of Input or Organization
France
INIS RN
11521801
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; DOSE-RESPONSE RELATIONSHIPS; FRACTIONATED IRRADIATION; INTESTINES; MICE; NEUTRONS; RBE; SURVIVAL CURVES
Descriptors DEC
ANIMALS; BARYONS; BIOLOGICAL EFFECTS; BODY; DIGESTIVE SYSTEM; ELEMENTARY PARTICLES; FERMIONS; GASTROINTESTINAL TRACT; HADRONS; IRRADIATION; MAMMALS; NUCLEONS; ORGANS; RADIATION EFFECTS; RODENTS; VERTEBRATES