Proliferation ability on bone marrow and thymus cells of rats treated with low doses of internal radiators
Description
In this article the dynamic retention of fission products 134Cs and 147Pm as well as the proliferation ability on cells of bone marrow and thymus of rats were investigated. The retention equation of 134Cs was well described by a two-exponential function, that is: R(t) = 18.04 e-9.3175 + 45.13 e-0.0423t. There are two retention components, fast and slow. The effective biological T1/2 were 0.07 and 16.14 days respectively. While the retention equation of 147Pm is: R(t) 0.199-e-0.1452t + 0.812 e-0.0008t. Where that fast component T1 was 4.77 d; and the slow component T2 was 866.3 d. Results show that the proliferation of bone marrow cells and thymus cells were excited with a low dose internal irradiation of 134Cs from 0.37 to 1.85 kBq/g and of 147Pm from 0.185 to 0.74 kBq/g. It showed that a stimulatory response of cell proliferation induced by low doses of 134Cs and 147Pm has been observed
Additional details
Publishing Information
- Journal Title
- Journal of Radiation Research and Radiation Processing
- Journal Volume
- 11
- Journal Issue
- 3
- Journal Page Range
- p. 171, 172-175.
- ISSN
- 1000-3436
- CODEN
- FYYXEA
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 25072741
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; BONE MARROW CELLS; CELL PROLIFERATION; CESIUM 134; INTERNAL IRRADIATION; LOW DOSE IRRADIATION; PROMETHIUM 147; RATS; STIMULATION; THYMOCYTES
- Descriptors DEC
- ANIMAL CELLS; ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; CESIUM ISOTOPES; CONNECTIVE TISSUE CELLS; ELECTRON CAPTURE RADIOISOTOPES; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; IRRADIATION; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; PROMETHIUM ISOTOPES; RADIATION EFFECTS; RADIOISOTOPES; RARE EARTH NUCLEI; RODENTS; SOMATIC CELLS; VERTEBRATES; YEARS LIVING RADIOISOTOPES