A kit for preparation of 188Re sulfide suspension

The 188Re sulfide suspension could be prepared quickly by a kit. The kit consists of three 10 mL vials. All the procedures were carried out in sterility circumstance. Vial A consisted of 1 mL KReO4 and Na2S2O3 (mole ratio 1:70) solution with excipient. Vial B was 5 mol/L HCl solution. Vial C consisted of 1.5 mL PVP and NaOH solution (mole ratio 1000:1). Vial B was sealed, Vial A and C were freeze-dried. Bacterium check, endotoxin check and security check were qualified. Kits were kept at ambient temperature and the Labelling efficiency of 188Re sulfide suspension was more than 98% with 2 months. The particle sizes were 1-5 μm (60.1 +- 12.7)%; 5-10 μm (30.9 +- 8.1)%; > 10 μm (9.0 +- 4.7)%. The radiochemical purity of 188Re sulfide suspension made by the kit was higher than 98% in 5 days with particle sizes 1-5 μm (49.9 +- 14.4%); 5-10 μm (41.1 +- 5.4)%; > 10μm (9.0 +- 3.3)%