Published October 2004 | Version v1
Journal article Metadata-only

Critical problems in the measurement and clinical evaluation of serum thyroglobulin and thyroglobulin antibody in differentiated thyroid cancer

Creators

  • 1. Shanghai Jiaotong Univ., Shanghai (China). Shanghai Sixth People's Hospital, Dept. of Nuclear Medicine

Description

Tg (thyroglobulin) is an established serum tumour marker in the follow-up of differentiated thyroid cancer. However, serum Tg measurement remains one of the most difficult biochemical tests for a laboratory to maintain to a high level of precision and reliability. TaAb (Tg antibody) interference is the most serious specificity problem affecting serum Tg measurement, regardless of the assay. This review presented an overview of the critical problems that should be taken into account in the measurements and clinical evaluation of serum Tg and TgAb in differentiated thyroid cancer. (author)

Additional details

Publishing Information

Journal Title
Foreign Medical Sciences. Section of Radiation Medicine and Nuclear Medicine
Journal Volume
28
Journal Issue
5
Journal Page Range
p. 197-199
ISSN
1001-098X

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
36107626
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
ANTIBODIES; BIOLOGICAL MARKERS; BLOOD SERUM; CARCINOMAS; IMMUNOASSAY; MEDICAL EXAMINATIONS; RADIOASSAY; RADIOIMMUNOASSAY; THYROGLOBULIN; THYROID; TSH
Descriptors DEC
BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY; BODY FLUIDS; DIAGNOSTIC TECHNIQUES; DISEASES; ENDOCRINE GLANDS; GLANDS; GLOBULINS; HORMONES; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; MEDICAL SURVEILLANCE; NEOPLASMS; ORGANIC COMPOUNDS; ORGANS; PEPTIDE HORMONES; PITUITARY HORMONES; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; TRACER TECHNIQUES

Optional Information

Notes
7 refs.