Published October 1984 | Version v1
Journal article Metadata-only

Effect of whole body hyperthermia and BCNU on the development of radiation myelitis in the rat

Creators

  • 1. Wisconsin Univ., Madison (USA). Dept. of Human Oncology
  • 2. Wisconsin Univ., Madison (USA)

Description

A radiant heat device was used to study the interaction of 41.80C whole body hyperthermia (WBH), x-radiation (40 Gy) and the lipophilic anti-neoplastic agent BCNU in the development of myelitis in the rat spinal cord. The addition of WBH and BCNU neither precipitated myelitis acutely nor shortened the latency before the onset of neurological signs in irradiated animals. (author)

Additional details

Publishing Information

Journal Title
Int. J. Radiat. Biol. Relat. Stud. Phys., Chem. Med.
Journal Volume
46
Journal Issue
4
Series
Int. J. Radiat. Biol. Relat. Stud. Phys., Chem. Med.
Journal Page Range
417-420
ISSN
0020-7616

INIS

Country of Publication
United Kingdom
Country of Input or Organization
United Kingdom
INIS RN
16030382
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; CHEMOTHERAPY; HYPERTHERMIA; MEDIUM TEMPERATURE; MYELITIS; RADIOTHERAPY; RATS; RESPONSE MODIFYING FACTORS; SPINAL CORD; X RADIATION
Descriptors DEC
ANIMALS; BIOLOGICAL EFFECTS; BODY TEMPERATURE; CENTRAL NERVOUS SYSTEM; DISEASES; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; MAMMALS; MEDICINE; NERVOUS SYSTEM; NERVOUS SYSTEM DISEASES; RADIATION EFFECTS; RADIATIONS; RODENTS; THERAPY; VERTEBRATES