Published 1988 | Version v1
Journal article

Radio-induced sarcomas in survivors of Ewing sarcoma

  • 1. Bologna Univ. (Italy). I Clinica Ortopedica
  • 2. Bologna Univ. (Italy). III Clinica Pediatrica
  • 3. Bologna Univ. (Italy). Dipt. di Radiologia
  • 4. Istituto Ortopedico Rizzoli, Bologna (Italy). Centro Tumori Ossei
  • 5. Istituto Ortopedico Rizzoli, Bologna (Italy). Dipt. di Medicina Interna

Description

Of 255 cases of Ewing's sarcoma recorded at the Bone Tumor Center of the Rizzoli Orthopaedic Institute, 78 patients (irradiated and with a follow-up of longer than3 years) were considered ''at risk'' for the development of a second radio-induced sarcoma (RIS). Three of the 78 patients developed an RIS in the irradiated field. Theoretical and statistical analyses were carried out considering different modalities of local treatment. Statistically, the only significant factor was related to the irradiation dose. Surgical resection seems to prevent RIS

Additional details

Publishing Information

Journal Title
Tumori
Journal Volume
75
Journal Issue
5
Series
Tumori.
Journal Page Range
543-551
ISSN
0300-8916
CODEN
TUMOA

Optional Information

Notes
17 refs.