Metabolism, residues and excretion of the anthelminthic 131I-rafoxanide in blood, milk, meat and urine at the lactating cow

Rafoxanide, labelled by 131I, was applied orally in the formulation 'Ursovermit' to 2 lactating cows, 5 mg/kg bodymass, respectively. Residues and half-lives in blood, milk and meat and the excretion in urine are given, related to 131I in the chloroform extract. 3,5-diiodosalicyclic acid was found as metabolite in amounts of 1-2,5%, relative to rafoxanide. (author)