Computed tomographic diagnosis of splenic and hepatic damages in malignant non-Hodgkin's lymphomas

Seventy eight patients with varying malignancy non-Hodgkin's lymphomas were examined. Signs of extranodal damage of the spleen and liver were studied. Spleno- and hepatomegalia were signs of the commonest diffuse visceral involvements. In terms of the malignancy (low- or high-grade), splenomegalia was seen in 71.4 and 82.5 % of patients and hepatomegalia was observed in 43.9 and 28.6 %, respectively. In addition, irregular visceral outlines, tuberosity, changed density of the parenchyma and its homogeneity. A high correlation was found between the enlargement of the viscera and their decreased parenchymal density. Focal visceral involvements are less difficult to be diagnosed than diffuse ones, but they are much rarer. Computerized tomographic findings indicate the malignancy of a process