Detection of hypoxanthine, xanthine and uric acid in γ-irradiated aqueous solution of cytosine
Creators
- 1. Nihon Univ., Tokyo. Coll. of Agriculture and Veterinary Medicine
Description
The aqueous solution of cytosine of 3.6 x 10-2 M was irradiated with gamma -ray (60 megarad) in nitrogen-saturated glass ampules, and freeze-dried, then the residue obtained was changed to trimethylsilylacid, and this was analyzed by paper chromatography, UV spectrometry, and/or gas-liquid chromatography. Hypoxanthine, xanthine and uric acid were detected in this solution, in addition to some other compounds already known to be produced by gamma -irradiation, e.g., TMS-uracil, TMS-6-hydroxyuracil and TMS-hypoxanthine. It was presumed that these compounds were formed by the recombination of the primary radiolytic products. Uric acid formation by this mechanism was confirmed by gamma -irradiation of the mixture that contained urea, and 5- and 6-hydroxyuracil. (Kaihara, S.)
Additional details
Publishing Information
- Journal Title
- Nippon Nogeikagaku Kaishi
- Journal Volume
- 53
- Journal Issue
- 10
- Series
- Nippon Nogeikagaku Kaishi.
- Journal Page Range
- 355-357
- ISSN
- 0002-1407
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 11569167
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- AQUEOUS SOLUTIONS; CHEMICAL RADIATION EFFECTS; CHEMICAL REACTION YIELD; CYTOSINE; GAMMA RADIATION; GAS CHROMATOGRAPHY; HYPOXANTHINE; IRRADIATION; ULTRAVIOLET SPECTRA; URIC ACID
- Descriptors DEC
- AMINES; AZINES; CHROMATOGRAPHY; DISPERSIONS; ELECTROMAGNETIC RADIATION; HETEROCYCLIC COMPOUNDS; HOMOGENEOUS MIXTURES; HYDROXY COMPOUNDS; IONIZING RADIATIONS; MIXTURES; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; PURINES; PYRIMIDINES; RADIATION EFFECTS; RADIATIONS; SEPARATION PROCESSES; SOLUTIONS; SPECTRA; XANTHINES