Published April 1989 | Version v1
Journal article Metadata-only

Factors affecting serum sialic acid levels

Creators

  • 1. Akademie der Wissenschaften der DDR, Berlin (German Democratic Republic). Zentralinstitut fuer Krebsforschung

Description

Inoculation of certain immunostimulators (BCG, Freund's adjuvant) as well as several antigens or Silasorb resulted in a 2- to 3-fold increase of the serum sialic acid level in mice. In contrast, treatments causing immunosuppression, like γ radiation and application of cyclophosphamide, did not influence the serum sialic acid level. Furthermore, immunosuppression did not prevent the increase caused by immunostimulators. The results suggest that macrophages may be involved in regulating the serum sialic acid levels after immunostimulation. (author)

Additional details

Publishing Information

Journal Title
Biomedica Biochimica Acta
Journal Volume
48
Journal Issue
4
Series
Biomed. Biochim. Acta.
Journal Page Range
365-369
ISSN
0232-766X
CODEN
BBIAD

INIS

Country of Publication
Germany
Country of Input or Organization
German Democratic Republic
INIS RN
20065686
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Descriptors DEI
BIOLOGICAL RADIATION EFFECTS; BLOOD SERUM; COBALT 60; GAMMA RADIATION; MICE; SIALIC ACID
Descriptors DEC
ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY FLUIDS; CARBOHYDRATES; COBALT ISOTOPES; ELECTROMAGNETIC RADIATION; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IONIZING RADIATIONS; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; MAMMALS; MATERIALS; MINUTES LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; POLYSACCHARIDES; RADIATION EFFECTS; RADIATIONS; RADIOISOTOPES; RODENTS; SACCHARIDES; VERTEBRATES; YEARS LIVING RADIOISOTOPES