Published 1985
| Version v1
Journal article
Low oxygen enhancement ratios for strand breaks induced by decays of 125I in DNA of human T1 cells stored at 0 deg C
- 1. Kernforschungsanlage Juelich G.m.b.H. (Germany, F.R.). Inst. fuer Medizin
Description
After incorporation of 125I into DNA of T1 cells, these cells were transferred into serum free medium where decays of 125I were accumulated at 00C under aerobic or hypoxic conditions. The unwinding technique was used for strand break measurements with ethidium bromide as a marker for double stranded DNA. Exposure of the cells to 1,500-14,000 decays, over periods of 4-7 days, gave an OER close to 1. Ideas about the nature of this phenomenon are discussed. (author)
Additional details
Publishing Information
- Journal Title
- Radiat. Prot. Dosim.
- Journal Volume
- 13
- Journal Issue
- 1-4
- Series
- Radiat. Prot. Dosim.
- Journal Page Range
- 237-239
- ISSN
- 0144-8420
- CODEN
- RPDOD
Conference
- Title
- 9. symposium on microdosimetry.
- Dates
- 20-24 May 1985.
- Place
- Toulouse (France).
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 17043507
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- AEROBIC CONDITIONS; ANAEROBIC CONDITIONS; ANIMAL CELLS; BETA DECAY; BIOLOGICAL RADIATION EFFECTS; CELL CULTURES; DNA; IODINE 125; OXYGEN ENHANCEMENT RATIO; RADIONUCLIDE KINETICS; STRAND BREAKS
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BIOLOGICAL EFFECTS; DAYS LIVING RADIOISOTOPES; DECAY; ELECTRON CAPTURE RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTO; IODINE ISOTOPES; ISOTOPES; KINETICS; NUCLEAR DECAY; NUCLEI; NUCLEIC ACIDS; ODD-EVEN NUCLEI; ORGANIC COMPOUNDS; RADIATION EFFECTS; RADIOISOTOPES