Inverted-V shaped FDG uptake is a clue for the diagnosis of IgG4-related prostatitis

We investigated the utility of inverted-V shaped FDG uptake in the PET diagnosis of IgG4-related prostatitis. For 25 males with IgG4-related disease (IgG4-RD) and 22 males with benign prostatic hyperplasia who had PET/CT checkup, the shape of prostatic uptake were compared as well as prostatic SUVmax. Then SUVmax was compared using ANOVA among the IgG4-RD cases with inverted-V uptake, those without inverted-V, and the controls. 10/25 IgG4-RD cases and 0/22 controls had inverted-V shaped uptake. Their SUVmax had a substantial overlap. ANOVA showed significant difference among the 3 groups, and inverted-V ( + ) cases had significantly higher SUVmax than inverted-V ( - ) IgG4-RD cases and the controls. Inverted-V uptake is useful for IgG4-RD diagnosis. (author)