Published 1982
| Version v1
Journal article
The short effect of pelvic radiotherapy of gynecological cancers on humoral and cell mediated immunity
Creators
- 1. Laboratoire d'Immunologie, C.H.U. Grenoble
- 2. Centre d'Etudes Nucleaires de Grenoble, 38 (France)
Description
An analysis of short effect of pelvic irradiation on cellular and humoral immunity was made in 24 patients treated by irradiation alone or a combination of surgery and irradiation for uterine carcinoma, at 2, 6, 12 months after loco-regional therapy. Twelve months later there is a decrease of T lymphocytes (P = 0.01), whereas the B lymphocytes count is normal; the percentage of T and B lymphocytes remains stable, but the lymphocyte response to PHA after 3 days is reduced (p = 0.03). A significant decrease of immunoglobulins G, A and M is observed
Additional details
Publishing Information
- Journal Title
- Biomed. Pharmacother.
- Journal Volume
- 36
- Journal Issue
- 3
- Series
- Biomed. Pharmacother.
- Journal Page Range
- 139-144
- ISSN
- 0300-0893
INIS
- Country of Publication
- France
- Country of Input or Organization
- France
- INIS RN
- 14749796
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Numerical Data
- Descriptors DEI
- EXPERIMENTAL DATA; IMMUNOGLOBULINS; IMMUNOSUPPRESSION; LYMPHOCYTES; PELVIS; RADIOTHERAPY; SIDE EFFECTS
- Descriptors DEC
- ANIMAL CELLS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BODY; BODY AREAS; BODY FLUIDS; CONNECTIVE TISSUE CELLS; DATA; GLOBULINS; INFORMATION; LEUKOCYTES; MATERIALS; MEDICINE; NUMERICAL DATA; ORGANIC COMPOUNDS; PROTEINS; SOMATIC CELLS; THERAPY