Published September 1984
| Version v1
Journal article
In situ radiation response and oxygen enhancement ratio of KHT sarcoma cells in various phases of the cell cycle
Description
Studies were made of the γ-radiation response across the cell cycle of KHT sarcoma cells grown as solid tumours. The most radioresistant portion of the cell cycle was found to be late G1 and early S. G2M cells were always most radiosensitive. Complete radiation dose-response curves under oxic or anoxic conditions were also obtained for cells in all phases of the cell cycle. From these the oxygen enhancement ratio (OER) was calculated to be 2.4, 2.6 and 2.5 for cells in the G1, S and G2M cell cycle phases respectively. (author)
Additional details
Publishing Information
- Journal Title
- Br. J. Radiol.
- Journal Volume
- 57
- Journal Issue
- 682
- Series
- Br. J. Radiol.
- Journal Page Range
- 823-827
- ISSN
- 0007-1285
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 16013553
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- CELL CYCLE; DOSE-RESPONSE RELATIONSHIPS; GAMMA RADIATION; OXYGEN ENHANCEMENT RATIO; RADIOSENSITIVITY; RESPONSE MODIFYING FACTORS; SARCOMAS; TUMOR CELLS
- Descriptors DEC
- ANIMAL CELLS; DISEASES; ELECTROMAGNETIC RADIATION; IONIZING RADIATIONS; NEOPLASMS; RADIATIONS