Creation of the technology and man's gen-engineering insulin extraction (GEIE) on the basis of high productive strain - GEIE producent

Main problems which should be solved: - To create the new highly productive recombinant GENI stain-producer - To select the medium and cultivation's conditions for stain-producer. - To elaborate the separation and purification GENI technology. In order to create the new GENI stain-producer we need significantly change the separation and purification's technology which was elaborated according to traditional method before. The separation and purification GENI's technology demand the industrial methods utilization, such as: ultrafiltration, high-and-low pressures chromatography. Besides, the utilization of recombinant micro-organisms, required for to obtain the medicinal preparations, places a constraint on the quality controls ready made product which should be in conformity with following conditions: high trustworthiness, reproducibility and sensitivity. In this connection, we need to perform a series of the work concerning with analytic controls methods of production and substance preparations technology. To create the separation and purification GENt technology on the highly productive recombinant GENI Stain-producers base. To put in an application in order to patient this new stain. The results of these works will be base for to prepare the normative-technical documents concerning with GENI substances production. Also, we will make the initial data and plan required for to project the GENI substances production. This work will be performed without foreign partner's participation