A histopathological study of spontaneous Wistar rat mammary tumor. The relation of the histopathological findings and X-ray CT image

The spontaneous malignant mammary tumor of Wistar female rat is relatively rare. The study of the tumor has not been performed from the histopathological and radiological points of view, especially in comparison with histopathological and X-ray CT findings. We examined the spontaneous mammary tumor of a 28 weeks Wistar female rat and studied it to make clear the relationship between histopathological findings and X-ray CT images. The results obtained were as follows; 1. Histopathologically, the necrosis and calcification were observed in the mammary tumor. These findings corresponded to the low density and several high density foci in the precontrast X-ray CT image of the mammary tumor. 2. Histopathologically, the nodular tubular pattern with separation of vascular fibrous tissue was observed in the tumor. The finding was corresponded to the position marked enhancement in the postcontrast CT image. (author)