MR imaging, flow and motion

The present work is intended as a nonmatheamtical review of the role of flow and motion in nuclear magnetic resonannce (MR) imaging. A historical review of MR flow measurement techniques is given, followed by a short overview of flow models in vitro and vivo. The theory behind the influence of motion on the modulus and phase MR signal information is discussed and effects such as washin/washout, flow-induced signal void, phase offset, and phase dispersion are defined. A simple approach to the concept of MR angiography is given, and methods for quantitative flow measurements such as the phase mapping technique, are surveyed. Aspects of the measurement of diffusion and microcirculation are given, and finally, an overview of the role of MR flow imaging in present and future clinical application is given. (orig.) With 143 refs