Published October 1981
| Version v1
Journal article
Photochemistry of pyrimidine bases as studied by e.s.r. and spin-trapping
Description
The direct photoexcitation of pyrimidine bases in D2O solutions yields free radicals which could be conveniently identified by spin-trapping with 2-methyl-2-nitrosopropane. Most of the radicals formed were attributed to D-addition to one end of the 5,6 double bond. However, orotic acid and iso-orotic acid yielded N(3) centred free radicals, formed by homolytic cleavage of the N-H bond. No indication could be found for a free radical involvement in the photocleavage of cyclobutane-type pyrimidine dimers. (author)
Additional details
Publishing Information
- Journal Title
- Int. J. Radiat. Biol. Relat. Stud. Phys., Chem. Med.
- Journal Volume
- 40
- Journal Issue
- 4
- Series
- Int. J. Radiat. Biol. Relat. Stud. Phys., Chem. Med.
- Journal Page Range
- 385-395
- ISSN
- 0020-7616
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 13653382
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL RADIATION EFFECTS; ELECTRON SPIN RESONANCE; HEAVY WATER; NITROSO COMPOUNDS; OROTIC ACID; PHOTOLYSIS; PROPANE; RADICALS; SOLUTIONS
- Descriptors DEC
- ALKANES; AZINES; BIOLOGICAL EFFECTS; CARBOXYLIC ACIDS; CHEMICAL REACTIONS; DECOMPOSITION; DISPERSIONS; HETEROCYCLIC ACIDS; HETEROCYCLIC COMPOUNDS; HOMOGENEOUS MIXTURES; HYDROCARBONS; HYDROGEN COMPOUNDS; HYDROXY COMPOUNDS; MAGNETIC RESONANCE; MIXTURES; ORGANIC ACIDS; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; OXYGEN COMPOUNDS; PYRIMIDINES; RADIATION EFFECTS; RESONANCE; URACILS; WATER