Published October 1986
| Version v1
Journal article
Suppressive effects of coffee on the SOS responses induced by UV and chemical mutagens
- 1. Osaka Prefectural Inst. of Public Health, Nakamichi-1, Higashinari-ku, Osaka (Japan)
Description
SOS-inducing activity of UV or chemical mutagens was strongly suppressed by instant coffee in Salmonella typhimurium TA1535/pSK1002. As decaffeinated instant coffee showed a similarly strong suppressive effect, it would seem that caffeine, a known inhibitor of SOS responses, is not responsible for the effect observed. The suppression was also shown by freshly brewed coffee extracts. However, the suppression was absent in green coffee-bean extracts. These results suggest that coffee contains some substance(s) which, apart from caffeine, suppresses SOS-inducing activity of UV or chemical mutagens and that the suppressive substance(s) are produced by roasting coffee beans. (Auth.)
Additional details
Publishing Information
- Journal Title
- Mutat. Res. Lett.
- Journal Volume
- 175
- Journal Issue
- 2
- Series
- Mutat. Res. Lett.
- Journal Page Range
- 47-50
- ISSN
- 0165-7992
- CODEN
- MUREA
INIS
- Country of Publication
- Netherlands
- Country of Input or Organization
- Netherlands
- INIS RN
- 18031400
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BEVERAGES; DNA REPAIR; MUTAGENS; RESPONSE MODIFYING FACTORS; SALMONELLA TYPHIMURIUM; ULTRAVIOLET RADIATION
- Descriptors DEC
- BACTERIA; BIOLOGICAL RECOVERY; BIOLOGICAL REPAIR; ELECTROMAGNETIC RADIATION; FOOD; MICROORGANISMS; RADIATIONS; SALMONELLA
Optional Information
- Notes
- 14 refs.; 3 figs.