Published 1986
| Version v1
Book
Characterization of (3H)-nicotine binding in rodent brain and comparison with the binding of other labelled nicotinic ligands
Description
In an investigation of the receptor through which nicotine exerts its central actions, radioactively labelled nicotine was used in biochemical in vitro binding studies. Tritium-labelled nicotine (tritium-NIC) binding to mouse hippocampus was studied and the effect of temperature on the binding was analyzed by saturation-binding experiments. The specific tritium-NIC binding was found to be approximately four times higher at 4 C than at 25 C
Additional details
Publishing Information
- Publisher
- Plenum Press.
- Imprint Place
- New York, NY (USA)
- Imprint Title
- Dynamics of cholinergic Function
- Journal Page Range
- p. 429-437.
Conference
- Title
- Conference on dynamics of cholinergic function.
- Dates
- 31 Oct - 4 Nov 1983.
- Place
- Ogle Bay Park, WV (USA).
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 18056497
- Subject category
- S60: APPLIED LIFE SCIENCES;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- BIOCHEMICAL REACTION KINETICS; BIOCHEMISTRY; BIOLOGICAL EFFECTS; HIPPOCAMPUS; LABELLING; LIGANDS; MICE; NERVE CELLS; NICOTINE; RADIORECEPTOR ASSAY; RECEPTORS; TEMPERATURE DEPENDENCE; TRITIUM COMPOUNDS
- Descriptors DEC
- ALKALOIDS; AMINES; ANIMAL CELLS; ANIMALS; AZINES; AZOLES; BODY; BRAIN; CENTRAL NERVOUS SYSTEM; CHEMISTRY; HETEROCYCLIC COMPOUNDS; HYDROGEN COMPOUNDS; ISOTOPE APPLICATIONS; KINETICS; MAMMALS; NERVOUS SYSTEM; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANS; PYRIDINES; PYRROLES; PYRROLIDINES; REACTION KINETICS; RODENTS; SOMATIC CELLS; TRACER TECHNIQUES; VERTEBRATES