Published 1993
| Version v1
Journal article
New kit for the preparation of 99mTcMAG3
Creators
- 1. Centro de Estudios Aplicados al Desarrollo Nuclear (CEADEN), La Habana (Cuba)
Description
A new kit for the preparation of 99mTc-MAG3 that consist in four vials has been developed. Two vials contains in freeze dried, sterile and non pyrogenic form a formulation with 0.65 mg of Benzoyl-MAG3 (synthesized by reaction of chloroacetiltriglycine with sodium tiobenzoate), 16 mg of sodium gluconate and 0,1 mg of stannous chloride dehydrated. One vial contains Na2HPO4 0,07 M pH 9,0-10,4 (Buffer No 1) for the adjust pH during the labelling process and another vial contains PBS pH 6,5-7,5 (Buffer No 2) for the adjust of pH after labeling process. Labeling with 99mTc is made by addition buffer No 1, boiling at 100oC during 15 minutes an addition of buffer No 2. Radiochemical purity obtained by this way is suitable for human use
Additional details
Additional titles
- Original title (Spanish)
- Nuevo kit para la preparacion de
Publishing Information
- Journal Title
- Nucleus (Havana)
- Journal Issue
- no.15
- Journal Page Range
- p. 23-26.
- ISSN
- 0864-084X
- CODEN
- NCLSEY
INIS
- Country of Publication
- Cuba
- Country of Input or Organization
- Cuba
- INIS RN
- 25020994
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- CHEMICAL PREPARATION; CHROMATOGRAPHY; DIAGNOSIS; KIDNEYS; LABELLING; QUALITY CONTROL; RADIOPHARMACEUTICALS; RATS; TECHNETIUM COMPLEXES; TECHNETIUM 99
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BODY; COMPLEXES; CONTROL; DRUGS; HOURS LIVING RADIOISOTOPES; INTERMEDIATE MASS NUCLEI; INTERNAL CONVERSION RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; MAMMALS; MATERIALS; NUCLEI; ODD-EVEN NUCLEI; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; SEPARATION PROCESSES; SYNTHESIS; TECHNETIUM ISOTOPES; TRANSITION ELEMENT COMPLEXES; VERTEBRATES; YEARS LIVING RADIOISOTOPES