Published July 14, 2006 | Version v1
Journal article Metadata-only

Preparation of quantum dot-coated magnetic polystyrene nanospheres for cancer cell labelling and separation

Creators

  • 1. Institute of Life Science and Technology, Tongji University, Shanghai 200092 (China)
  • 2. Institute of Life Science and Technology, Shanghai Jiaotong University, Shanghai 200032 (China)

Description

CdTe-coated magnetic polystyrene nanospheres (MPN) were prepared via a stepwise electrostatic self-assembly approach, and the conjugation of epidermal growth factor (EGF) to the MPN/CdTe core-shell nanocomposites was prepared by using 1-ethyl-3(3-dimethylamino propyl)-carbodiimide (EDC) as a cross-linking reagent. The MPN/CdTe and their bioconjugates yielded not only emitted bright fluorescence, but also exhibited superparamagnetism. The human breast cancer MDA-MB-435S cells could be labelled and rapidly separated by the MPN/CdTe-EGF bioconjugates. These magnetofluorescent nanospheres, consisting of magnetic spheres and quantum dots (QDs), may be of special interest for many biomedical applications

Availability note (English)

Available online at http://stacks.iop.org/0957-4484/17/3268/nano6_13_032.pdf or at the Web site for the journal Nanotechnology (Print) (ISSN 1361-6528 ) http://www.iop.org/

Additional details

Identifiers

URL
http://stacks.iop.org/0957-4484/17/3268/nano6_13_032.pdf; http://www.iop.org/;
DOI
10.1088/0957-4484/17/13/032;
PII
S0957-4484(06)18962-X;

Publishing Information

Journal Title
Nanotechnology (Print)
Journal Volume
17
Journal Issue
13
Journal Page Range
p. 3268-3273
ISSN
0957-4484

INIS

Country of Publication
United Kingdom
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
38007100
Subject category
S71: CLASSICAL AND QUANTUM MECHANICS, GENERAL PHYSICS;
Descriptors DEI
CADMIUM TELLURIDES; COMPOSITE MATERIALS; CROSS-LINKING; FLUORESCENCE; GROWTH FACTORS; LABELLING; MAMMARY GLANDS; NEOPLASMS; POLYSTYRENE; QUANTUM DOTS; SUPERPARAMAGNETISM
Descriptors DEC
BODY; CADMIUM COMPOUNDS; CHALCOGENIDES; CHEMICAL REACTIONS; DISEASES; EMISSION; GLANDS; LUMINESCENCE; MAGNETISM; MATERIALS; MITOGENS; NANOSTRUCTURES; ORGANIC COMPOUNDS; ORGANIC POLYMERS; ORGANS; PETROCHEMICALS; PETROLEUM PRODUCTS; PHOTON EMISSION; PLASTICS; POLYMERIZATION; POLYMERS; POLYOLEFINS; POLYVINYLS; PROTEINS; SYNTHETIC MATERIALS; TELLURIDES; TELLURIUM COMPOUNDS