Published March 2017 | Version v1
Journal article Metadata-only

Cost-effectiveness of prophylactic cranial irradiation with hippocampal avoidance in limited stage small cell lung cancer

Creators

  • 1. Queen's University, Kingston, ON (Canada)
  • 2. University of Maryland, Baltimore, MD (United States)
  • 3. London Health Sciences Center, ON (Canada)
  • 4. VU University Medical Center, Amsterdam (Netherlands)
  • 5. Miami Cancer Institute, FL (United States)
  • 6. Northwestern Medicine Cancer Chicago Center Warrenville and Northwestern Medicine Chicago Proton Center, Northwestern University, IL (United States)

Description

Background and purpose: Prophylactic cranial irradiation (PCI) in limited stage small cell lung cancer (LS-SCLC) prevents brain metastases and improves survival, with the potential for neurocognitive toxicity. RTOG0933 demonstrated that hippocampal avoidance (HA) during whole brain radiotherapy preserves neurocognition. This study's objective was to evaluate the cost-effectiveness of HA-PCI in LS-SCLC through decision analysis.

Availability note (English)

Available from http://dx.doi.org/10.1016/j.radonc.2017.01.005

Additional details

Identifiers

DOI
10.1016/j.radonc.2017.01.005;
PII
S0167814017300105;

Publishing Information

Journal Title
Radiotherapy and Oncology
Journal Volume
122
Journal Issue
3
Journal Page Range
p. 411-415
ISSN
0167-8140
CODEN
RAONDT

INIS

Country of Publication
Ireland
Country of Input or Organization
International Atomic Energy Agency (IAEA)
INIS RN
50080999
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BRAIN; COST EFFECTIVENESS ANALYSIS; LUNGS; METASTASES; NEOPLASMS; RADIOTHERAPY; TOXICITY
Descriptors DEC
BODY; CENTRAL NERVOUS SYSTEM; DISEASES; ECONOMIC ANALYSIS; ECONOMICS; MEDICINE; NERVOUS SYSTEM; NUCLEAR MEDICINE; ORGANS; RADIOLOGY; RESPIRATORY SYSTEM; THERAPY

Optional Information

Copyright
Copyright (c) 2017 Elsevier Science B.V., Amsterdam, The Netherlands, All rights reserved.