Diagnostic value of combined measurement of serum CEA, AFP, CA19-9 and SA levels in patients with primary hepatic cancer
Creators
- 1. Department of Laboratory, Lianyungang Second Municipal People's Hospital, Lianyungang (China)
Description
Objective: To study the diagnostic value of combined measurement of serum CEA, AFP, CA19-9 and SA levels for primary hepatic cancer. Methods: Serum CEA, AFP, CA19-9 (with RIA) SA (with biochemistry) levels were measured in 36 patients with primary hepatic cancer and 35 controls. Results: As a single tumor marker for diagnosis, the sensitivity of CEA, AFP, CA19-9, SA was 33.3%, 69.4%, 58.5% and 61.1% respectively, the specificity was 60.4%, 81.3% 68.8%, 64.4% respectively. With combined detection of the four markers and assuming two or more markers positive as positive, the sensitivity would be 94.4% and specificity would be 95.8%. Conclusion: Combined measurement of serum CEA, AFP, CA19-9 and SA levels is of clinical usefulness for diagnosis of primary hepatic cancer. (authors)
Additional details
Publishing Information
- Journal Title
- Journal of Radioimmunology
- Journal Volume
- 23
- Journal Issue
- 3
- Journal Page Range
- p. 266-267
- ISSN
- 1008-9810
INIS
- Country of Publication
- China
- Country of Input or Organization
- China
- INIS RN
- 44076122
- Subject category
- S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Descriptors DEI
- BLOOD SERUM; CARCINOEMBRYONIC ANTIGEN; DETECTION; DIAGNOSIS; GLOBULINS-ALPHA; GLYCOPROTEINS; HEPATOMAS; LIVER; PATIENTS; RADIOIMMUNOASSAY; SENSITIVITY; SIALIC ACID; SPECIFICITY
- Descriptors DEC
- ANTIGENS; BIOASSAY; BIOLOGICAL MATERIALS; BLOOD; BLOOD PLASMA; BODY; BODY FLUIDS; CARBOHYDRATES; CARCINOMAS; DIAGNOSTIC TECHNIQUES; DIGESTIVE SYSTEM; DISEASES; GLANDS; GLOBULINS; IMMUNOASSAY; ISOTOPE APPLICATIONS; MATERIALS; NEOPLASMS; ORGANIC COMPOUNDS; ORGANS; PROTEINS; RADIOASSAY; RADIOIMMUNODETECTION; SACCHARIDES; TRACER TECHNIQUES
Optional Information
- Notes
- 3 tabs., 8 refs.