Published 1990
| Version v1
Report
Synthesis of iodine-123 labeled 3-O-(E)-3-iodopropen-2-yl-D-glucose: A potential new agent for the assessment of glucose transport into the brain and heart using SPECT
- 1. Univ. of Tennessee, Knoxville (United States)
Description
The authors have developed a synthesis of iodine-123 labelled 3-O-(E)-3-iodopropen-2-yl-D-glucose as an analogue of carbon-11 labelled 3-O-methyl-D-glucose, with the objective of achieving high brain and heart uptake. The four reaction steps in the synthesis are discussed and tissue distributions in rats will be presented
Additional details
Publishing Information
- Imprint Title
- Eighth international symposium on radiopharmaceutical chemistry. Abstracts: Final report
- Imprint Pagination
- 458 p.
- Journal Page Range
- p. 285-286.
- Report number
- DOE/ER/60968--1
Conference
- Title
- 8. international symposium on radiopharmaceutical chemistry.
- Dates
- 24-29 Jun 1990.
- Place
- Princeton, NJ (United States).
INIS
- Country of Publication
- United States
- Country of Input or Organization
- United States
- INIS RN
- 23029806
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY; S62: RADIOLOGY AND NUCLEAR MEDICINE;
- Resource subtype / Literary indicator
- Conference, Non-conventional Literature
- Descriptors DEI
- BLOOD-BRAIN BARRIER; BRAIN; CELL MEMBRANES; CHEMICAL PREPARATION; CHEMICAL REACTION YIELD; FLUORINE 18; FLUORODEOXYGLUCOSE; GLUCOSE; HEART; HEXOSES; HOURS LIVING RADIOISOTOPES; HYDROLYSIS; IODINE 123; LABELLING; MEMBRANE TRANSPORT; MOLECULAR STRUCTURE; POSITRON COMPUTED TOMOGRAPHY; RADIOPHARMACEUTICALS; RATS; TISSUE DISTRIBUTION; UPTAKE
- Descriptors DEC
- ALDEHYDES; ANIMALS; ANTIMETABOLITES; BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; BODY; CARBOHYDRATES; CARDIOVASCULAR SYSTEM; CELL CONSTITUENTS; CENTRAL NERVOUS SYSTEM; CHEMICAL REACTIONS; COMPUTERIZED TOMOGRAPHY; DECOMPOSITION; DISTRIBUTION; DRUGS; ELECTRON CAPTURE RADIOISOTOPES; EMISSION COMPUTED TOMOGRAPHY; FLUORINE ISOTOPES; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MAMMALS; MATERIALS; MEMBRANES; MONOSACCHARIDES; NANOSEC LIVING RADIOISOTOPES; NERVOUS SYSTEM; NUCLEI; ODD-EVEN NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANS; RADIOACTIVE MATERIALS; RADIOISOTOPES; RODENTS; SACCHARIDES; SOLVOLYSIS; SYNTHESIS; TOMOGRAPHY; VERTEBRATES
Optional Information
- Secondary number(s)
- CONF-9006363--Absts.