Published November 1979 | Version v1
Journal article Metadata-only

Indication of radioresistance modified by radioprotective agents

Creators

Description

In experiments on rats a study was made of hypoxic and radioprotective effectiveness of mexamine in bone marrow. It was shown that radioprotective effectiveness of hypoxia decreases 45-60 min after administration of the protective agents. The regulatory-metabolic conception is expounded which attributes the observed phenomenon to the increase in the intracellular oxygen concentration and normalization of recovery of internal cell medium

Additional details

Additional titles

Subtitle (English)
Rep. 2. Correlation between hypoxic and radioprotective effect of 5-methoxytryptamine administered before irradiation
Original title (Russian)
Вопросы индикации модифицированной протекторами радиорезистентности
Original subtitle (Russian)
Soobshchenie 2. Sootnoshenie gipoksicheskogo i radiozashchitnogo ehffektov 5-metoksitriptamina pri otsrochennom ego vvedenii do oblucheniya.

Publishing Information

Journal Title
Radiobiologiya
Journal Volume
24
Journal Issue
6
Series
Radiobiologiya.
Journal Page Range
868-875
ISSN
0033-8192

INIS

Country of Publication
Russian Federation
Country of Input or Organization
USSR
INIS RN
11570065
Subject category
S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
Resource subtype / Literary indicator
Numerical Data
Descriptors DEI
ANOXIA; BONE MARROW CELLS; EXPERIMENTAL DATA; INTRAPERITONEAL INJECTION; MALES; MEXAMINE; RADIATION PROTECTION; RADIOSENSITIVITY; RATS; RESPONSE MODIFYING FACTORS; TIME DEPENDENCE; WHOLE-BODY IRRADIATION; X RADIATION
Descriptors DEC
AMINES; ANIMAL CELLS; ANIMALS; AZOLES; CONNECTIVE TISSUE CELLS; DATA; DRUGS; ELECTROMAGNETIC RADIATION; ETHERS; EXTERNAL IRRADIATION; HETEROCYCLIC COMPOUNDS; HYDROXY COMPOUNDS; INDOLES; INFORMATION; INJECTION; INTAKE; IONIZING RADIATIONS; IRRADIATION; MAMMALS; NUMERICAL DATA; ORGANIC COMPOUNDS; ORGANIC NITROGEN COMPOUNDS; ORGANIC OXYGEN COMPOUNDS; PYRROLES; RADIATIONS; RADIOPROTECTIVE SUBSTANCES; RODENTS; SEROTONIN; SOMATIC CELLS; SYMPATHOMIMETICS; TRYPTAMINES; VERTEBRATES

Optional Information

Notes
For English translation see the journal Radiobiology (USA).