Published March 2023 | Version v1
Journal article Metadata-only

Cesium distribution in renal tissues by high-energy synchrotron radiation X-ray fluorescence analysis

Creators

  • 1. National Institutes for Quantum Science and Technology, National Institute of Radiological Sciences, Chiba (Japan)
  • 2. Chiba University, Graduate School of Science, Chiba (Japan)

Description

To investigate cesium (Cs) distribution in tissues, high-energy synchrotron radiation X-ray fluorescence (SR-XRF) analysis with microprobe was applied to Cs imaging of mice renal specimens. Cs images were constructed using the intensity data of Cs Kα line (30.968 keV) at each point obtained by scanning the specimens with microbeam (1.0 μm x 1.0 μm, 37 keV). The detection limit evaluated with thin section standards of Cs was 6 μg/g (counting time, 10 sec). Clear images of Cs corresponding to fine tissue structures were obtained from renal specimens of mice exposed to Cs (50 mg/kg, oral). Cs was found in the medulla and the outer strip of the outer medulla. (author)

Abstract (Japanese)

生体組織試料でのセシウム(Cs)の分布様態を把握するため,マイクロビームを用いた高エネルギーシンクロトロン放射光蛍光X線(SR-XRF)分析によるマウス腎臓組織中Csイメージングを検討した.Csイメージングは37keVのマイクロビーム(1.0 µm x 1.0 µm)を用いて試料を走査し,Cs Kα線(30.968 keV)の検出により行った.薄切分析標準を用いて感度評価を行ったところ10秒計数あたりのCs検出下限は6 μg/gであった.Csを投与(50mg/kg,経口)したマウス腎臓についての測定では,腎臓の微細構造に対応したCsイメージングが得られた.その結果,Csは腎臓の髄質から髄質外辺部に多く分布していることが示された.(著者)

Additional details

Additional titles

Original title (Japanese)
高エネルギー放射光蛍光X線分析による腎臓組織中セシウム分布

Publishing Information

Journal Title
X-sen Bunseki No Shinpo
Journal Volume
54
Series
雑誌名:X線分析の進歩
Journal Page Range
p. 139-146
ISSN
0911-7806

INIS

Country of Publication
Japan
Country of Input or Organization
Japan
INIS RN
55015580
Subject category
S60: APPLIED LIFE SCIENCES; S37: INORGANIC, ORGANIC, PHYSICAL AND ANALYTICAL CHEMISTRY;
Descriptors DEI
BEAM MONITORS; BLOOD; CESIUM; ICP MASS SPECTROSCOPY; KIDNEYS; MICE; SEMICONDUCTOR DETECTORS; SPRING-8 STORAGE RING; SYNCHROTRON RADIATION; X-RAY FLUORESCENCE ANALYSIS
Descriptors DEC
ALKALI METALS; ANIMALS; BIOLOGICAL MATERIALS; BODY; BODY FLUIDS; BREMSSTRAHLUNG; CHEMICAL ANALYSIS; ELECTROMAGNETIC RADIATION; ELEMENTS; MAMMALS; MASS SPECTROSCOPY; MATERIALS; MEASURING INSTRUMENTS; METALS; MONITORS; NONDESTRUCTIVE ANALYSIS; ORGANS; RADIATION DETECTORS; RADIATION SOURCES; RADIATIONS; RODENTS; SPECTROSCOPY; STORAGE RINGS; SYNCHROTRON RADIATION SOURCES; VERTEBRATES; X-RAY EMISSION ANALYSIS

Optional Information

Notes
18 refs., 6 figs., 1 tab.