Clinicobiological basis of combined and multimodality treatment

General principles of combined and multimodality treatment of oncologic patients are formulated: given up the opposition of methods of antitumoral effect and their combinations; search for the most effective schemes of complex therapy, based on peculiarities of localization of morphologic structure, clinical and biological tumor characteristics, pathogenetic and prognostic factors; development of complex methods, providing both recovery of patients and their social and labour rehabilitation