Published June 2010
| Version v1
Report
The combination effects of PI3 kinase inhibitor and heavy ion irradiation
- 1. National Inst. of Radiological Sciences, Chiba, Chiba (Japan)
Description
The PI3K signaling pathway is activated by many types of stimuli and regulates fundamental cellular functions such as transcription, translation, proliferation, growth, and survival, and is up-regulated in many tumors. The antitumor effects by approaches of suppression of PI3K signaling have been shown in various cancer cells. In this study, we examined which PI3 kinase inhibitor functioned as radio-sensitizer using with heavy ion irradiation. (author)
Additional details
Identifiers
Publishing Information
- Imprint Title
- 2009 annual report of the research project with heavy ions at NIRS-HIMAC
- Imprint Pagination
- 338 p.
- Journal Page Range
- p. 62-63
- Report number
- NIRS-M--234
INIS
- Country of Publication
- Japan
- Country of Input or Organization
- Japan
- INIS RN
- 53066950
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Non-conventional Literature
- Descriptors DEI
- ABSORBED RADIATION DOSES; BIOLOGICAL RADIATION EFFECTS; CARBON IONS; COLONY FORMATION; GY RANGE 01-10; HEAVY IONS; HELA CELLS; RADIOSENSITIVITY; RADIOSENSITIZERS
- Descriptors DEC
- ABSORBED DOSE RANGE; ANIMAL CELLS; BIOLOGICAL EFFECTS; CHARGED PARTICLES; DOSES; DRUGS; GY RANGE; IONS; RADIATION DOSE RANGES; RADIATION DOSES; RADIATION EFFECTS; RESPONSE MODIFYING FACTORS; SENSITIVITY; TUMOR CELLS
Optional Information
- Notes
- This record replaces 45037357
- Secondary number(s)
- HIMAC--134