⁶⁸Ge/⁶⁸Ga composite CeO₂-PAN generator. Preparation, testing and use

This work is focused on the testing of a new ⁶⁸Ge/⁶⁸Ga radionuclide generator based on cerium dioxide in polyacrylonitrile beads. During an 18-month period, parameters of elution were monitored, and basic radiolabelling studies were carried out. As current commercial solutions deal with high elution volume and low long-term stability, the constructed system offers several improvements. The composite sorbent provides uniformity of active component dispersion and high capacity for ⁶⁸Ge. It enables minimal elution volume without fractionation (up to 1.8 mL) and stability of ⁶⁸Ge breakthrough (under 0.001%) after initial period of wash-out and low cerium leakage (under 5 ppm). (author)