Early decrease of PSA, a prognosis factor independent from biochemical control in case of remedial radiotherapy after prostatectomy

The authors report the analysis of the predictive value of PSA (prostate specific antigen) decrease during a remedial external radiotherapy performed to increase the PSA after a radical prostatectomy. During four years, 136 patients have been treated by external irradiation to obtain a PSA increase after prostatectomy. Different parameters are noticed: initial pathological stage, initial Gleason score, mean time between prostatectomy and external radiotherapy, values of PSA before and after prostatectomy and after radiotherapy. The evolution of PSA could be used for an early identification of patients presenting a pejorative prognosis. Short communication