Published July 2020 | Version v1
Journal article Metadata-only

"Negative T2 shine through" in patients with hyperglycemia and seizures. A frequently overlooked MRI pattern

Creators

  • 1. Department of Neuroradiology, Faculty of Medicine, Medical Center – University of Freiburg (Germany)
  • 2. Department of Neurology, Faculty of Medicine, Medical Center – University of Freiburg (Germany)
  • 3. Department of Neuroradiology, University Medical Center Bonn (Germany)
  • 4. Department of Neurology, University Medical Center Bonn (Germany)

Description

Epileptic seizures associated with hyperglycemia have a rare but characteristic MR imaging pattern which however is frequently missed. It consists of a T2 hypointensity and an apparent diffusion coefficient (ADC) decrease of the white matter underlying the epileptic cortex; the cortex itself may be DWI hyperintense and show a blood-brain barrier disruption. Prompt diagnosis is relevant since treatment of the hyperglycemic state rather than treatment with anti-epileptic drugs frequently interrupts the seizures. Subcortical T2 hypointensity and ADC decrease may be completely reversible.

Availability note (English)

Available from: http://dx.doi.org/10.1007/s00234-020-02408-w

Additional details

Identifiers

DOI
10.1007/s00234-020-02408-w;

Publishing Information

Journal Title
Neuroradiology
Journal Volume
62
Journal Issue
7
Journal Page Range
p. 895-899
ISSN
0028-3940
CODEN
NRDYAB

INIS

Country of Publication
Germany
Country of Input or Organization
Germany
INIS RN
51088245
Subject category
S62: RADIOLOGY AND NUCLEAR MEDICINE;
Descriptors DEI
BLOOD-BRAIN BARRIER; BRAIN; CONTRAST MEDIA; DIAGNOSIS; DIFFUSION; DRUGS; EPILEPSY; HYPERGLYCEMIA; IMAGE PROCESSING; MAGNETIC SUSCEPTIBILITY; NMR IMAGING; RELAXATION TIME; WEIGHTING FUNCTIONS
Descriptors DEC
BODY; CENTRAL NERVOUS SYSTEM; DIAGNOSTIC TECHNIQUES; DISEASES; FUNCTIONS; MAGNETIC PROPERTIES; NERVOUS SYSTEM; NERVOUS SYSTEM DISEASES; ORGANS; PHYSICAL PROPERTIES; PROCESSING