Published 1998
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Radiation pneumonitis: effect of long-term administration of Pentoxifylline and Dexamethasone on interstitial edema development
- 1. Katedra vojenske radiobiologie, Vojenska akademie J.E. Purkyne, Hradec Kralove (Czech Republic)
- 2. Fingerlanduv ustav patologie, Fakultni nemocnice, Hradec Kralove (Czech Republic)
Description
The thickness of alveolar septa in mice (C57BI/6 x DBA/2)F1 was examined 168 days after gamma irradiation of the lung region with a dose of 16 Gy and 180 days after irradiation with 18 Gy. Twice a week the animals were administered Pentoxiphylline (3.5 and 35 mg/kg), Dexamethasone (1 and 10 mg/kg) and their combination ((35 + 10) mg/kg). A significant decrease in the alveolar septum thickness was observed in all animals. The combination of the drugs was particularly efficacious
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Additional details
Additional titles
- Original title (Czech)
- Radiacni pneumonitida: vliv dlouhodobeho podavani Pentoxifylinu a Dexametazonu na rozvoj intersticialniho edemu
Publishing Information
- Imprint Title
- International Congress 'Laser and Medicine 98 and Radiobiological Symposium'. Programme and abstracts
- Imprint Pagination
- [43 p.]
- Journal Page Range
- p. 14
- Report number
- INIS-CZ--0017
Conference
- Title
- International Congress 'Laser and Medicine 98 and Radiobiological Symposium'
- Original Conference Title
- Mezinarodni kongres 'Laser a medicina 98 a Radiobiologicke symposium'
- Dates
- 21-23 May 1998
- Place
- Prague (Czech Republic)
INIS
- Country of Publication
- Czech Republic
- Country of Input or Organization
- Czech Republic
- INIS RN
- 30012282
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Resource subtype / Literary indicator
- Conference
- Descriptors DEI
- DELAYED RADIATION EFFECTS; DRUGS; LOCAL IRRADIATION; LUNGS; MICE; PNEUMONITIS; POST-IRRADIATION THERAPY
- Descriptors DEC
- ANIMALS; BIOLOGICAL EFFECTS; BIOLOGICAL RADIATION EFFECTS; BODY; IRRADIATION; MAMMALS; MEDICINE; ORGANS; RADIATION EFFECTS; RESPIRATORY SYSTEM; RODENTS; THERAPY; VERTEBRATES
Optional Information
- Notes
- Imprint:Mezinarodni kongres 'Laser a medicina 98 a Radiobiologicke symposium'. Program, sbornik abstrakt