Published May 2014 | Version v1
Journal article Metadata-only

Syntheses of stable isotope labeled D12-Malachite Green

Creators

  • 1. Shanghai Research Institute of Chemical Industry, Shanghai (China)

Description

The efficient synthesis of stable isotope labeled D12-Malachite Green with CD3OD as the precursor by methylation, condensation and oxidation was presented. The yields of D12-Malachite Green was 50.1% based on CD3OD consumed. The product was ideatified by HPLC, MS, and NMR to be the target compound. Its chemical purity and isotopic enrichment were higher than 99.0 atom% D. The result showed that the D12-Malachite Green could be used as internal standard in the field of food safety. (authors)

Additional details

Publishing Information

Journal Title
Journal of Isotopes
Journal Volume
27
Journal Issue
2
Journal Page Range
p. 77-81
ISSN
1000-7512

INIS

Country of Publication
China
Country of Input or Organization
China
INIS RN
51032338
Subject category
S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
Descriptors DEI
ENRICHMENT; HIGH-PERFORMANCE LIQUID CHROMATOGRAPHY; IMPURITIES; METHYLATION; NUCLEAR MAGNETIC RESONANCE; OXIDATION; SAFETY; STABLE ISOTOPES; SYNTHESIS
Descriptors DEC
CHEMICAL REACTIONS; CHROMATOGRAPHY; ISOTOPES; LIQUID COLUMN CHROMATOGRAPHY; MAGNETIC RESONANCE; RESONANCE; SEPARATION PROCESSES

Optional Information

Notes
3 figs., 16 refs.