Published January 1980
| Version v1
Journal article
131I Rose bengal clearance during hepatic regeneration in rats
Description
Intravenous I131 Rose bengal clearance was conducted in partially hepatectomized rats with a dose of 1 μCi/100 gm body weight. Blood samples were taken at regular intervals upto 25 minutes which were suitably diluted to count the remaining radioactivity. From these values t(1/2) and the clearance constants were worked out upto a period of 120 hr after partial hepatectomy. An analysis of the results show that there is a linear correlation between the Rose bengal clearance and the regenerating hepatic mass which may be used for quantitative assessment of functional hepatic mass. (author)
Additional details
Publishing Information
- Journal Title
- Indian J. Physiol. Pharmacol.
- Journal Volume
- 24
- Journal Issue
- 1
- Series
- Indian J. Physiol. Pharmacol.
- Journal Page Range
- 56-60
- ISSN
- 0019-5499
INIS
- Country of Publication
- India
- Country of Input or Organization
- India
- INIS RN
- 16006196
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BIOLOGICAL HALF-LIFE; BIOLOGICAL REGENERATION; HEPATECTOMY; INTRAVENOUS INJECTION; IODINE 131; LABELLED COMPOUNDS; LIVER; RADIONUCLIDE ADMINISTRATION; RATS; ROSE BENGAL; TRACER TECHNIQUES
- Descriptors DEC
- ANIMALS; BETA DECAY RADIOISOTOPES; BETA-MINUS DECAY RADIOISOTOPES; BIOLOGICAL RECOVERY; BODY; CARBOXYLIC ACIDS; DAYS LIVING RADIOISOTOPES; DIGESTIVE SYSTEM; DYES; GLANDS; HYDROXY ACIDS; INDICATORS; INJECTION; INTAKE; INTERMEDIATE MASS NUCLEI; IODINE ISOTOPES; ISOTOPE APPLICATIONS; ISOTOPES; MAMMALS; MEDICINE; NUCLEI; ODD-EVEN NUCLEI; ORGANIC ACIDS; ORGANIC CHLORINE COMPOUNDS; ORGANIC COMPOUNDS; ORGANIC HALOGEN COMPOUNDS; ORGANIC IODINE COMPOUNDS; ORGANS; RADIOISOTOPES; REAGENTS; RODENTS; SURGERY; VERTEBRATES
Optional Information
- Notes
- 5 refs.