Published 1990
| Version v1
Journal article
Extraction of [18F]fluoride from [18O]water by a fast fibrous anion exchange resin
- 1. Univ. of Michigan Medical School, Ann Arbor (USA). Division of Nuclear Medicine
Description
[18F]Fluoride for nucleophilic radiofluorination was recovered from target water by trapping on a fibrous anion exchange resin in the hydroxide form and subsequent displacement into wet methanolic K2CO3. Extraction into methanol facilitated rapid evaporation and resolubilization of the [18F]fluoride as an ion pair. The resin was first dried in situ and rehydrated with [18O]H2O to avoid isotopic dilution of the target water. (author)
Additional details
Publishing Information
- Journal Title
- Applied Radiation and Isotopes
- Journal Volume
- 41
- Journal Issue
- 6
- Series
- Appl. Radiat. Isot.
- Journal Page Range
- 583-586
- ISSN
- 0883-2889
- CODEN
- ARISE
INIS
- Country of Publication
- United Kingdom
- Country of Input or Organization
- United Kingdom
- INIS RN
- 21070227
- Subject category
- S38: RADIATION CHEMISTRY, RADIOCHEMISTRY AND NUCLEAR CHEMISTRY;
- Descriptors DEI
- FLUORINE 18; ION EXCHANGE; ISOTOPE PRODUCTION; OXYGEN 18 TARGET; RADIOPHARMACEUTICALS; RESINS
- Descriptors DEC
- BETA DECAY RADIOISOTOPES; BETA-PLUS DECAY RADIOISOTOPES; DRUGS; FLUORINE ISOTOPES; HOURS LIVING RADIOISOTOPES; ISOMERIC TRANSITION ISOTOPES; ISOTOPES; LABELLED COMPOUNDS; LIGHT NUCLEI; MATERIALS; NANOSEC LIVING RADIOISOTOPES; NUCLEI; ODD-ODD NUCLEI; ORGANIC COMPOUNDS; ORGANIC POLYMERS; POLYMERS; RADIOACTIVE MATERIALS; RADIOISOTOPES; TARGETS