Inter-element effects correction due to the secondary x-ray fluorescence in pixe analysis technic

For accurate determination of analyte concentration, on must take into account the effect of proton energy decrease and as a consequence a change in ionization cross sections as rthe beam penetrates the sample. Further one must also correct for matrix effects. This phenomena is due to the attenuation of the emerging X-rays from a major elements by a minor element which ha sa high coefficient absorption for this radiation. We present in this paper the work related to the developpement of a computer pragram for the estimation of such correction. We show the importance of this correction as function of the proton incident energy and of the sample type and its composition