Toxicological Studies Of Cyolane, Cytrolane And Curacron On Haematological And Testosterone Levels In Rats
Creators
- 1. Atomic Energy Authority , Cairo, (Egypt) Radioisotopes Department, Nuclear Nuclear Research Centre
Description
This study has been carried out to evaluate and compare the influence of (1/10 LD50) cyolane, cytrolane and curacron on male rats sex hormone (testosterone) and certain haematological parameters after daily oral administration for 4 weeks followed by 4 weeks withdrawal period. The data obtained revealed significant decrease in erythrocytic counts, haemoglobin concentration and in haematocrit value, withdrawal data showed no recovery in erythrocytic counts in cyolane treated group. In cytrolane and curacron treated groups, haemoglobin and haematocrit values were more or less recovered. All the used organophosphorus pesticides induced an increase in leucocyte counts which were higher than control even after withdrawal period. Testosterone was significantly decreased with no recovery tendency
Additional details
Publishing Information
- Journal Title
- Arab Journal of Nuclear Sciences and Applications
- Journal Volume
- 32
- Journal Issue
- 1
- Journal Page Range
- p. 233-239
- ISSN
- 1110-0451
INIS
- Country of Publication
- Egypt
- Country of Input or Organization
- Egypt
- INIS RN
- 31017925
- Subject category
- S63: RADIATION, THERMAL, AND OTHER ENVIRONMENTAL POLLUTANT EFFECTS ON LIVING ORGANISMS AND BIOLOGICAL MATERIALS;
- Descriptors DEI
- BLOOD SERUM; ERYTHROCYTES; INSECTICIDES; PESTICIDES; RATS; TESTOSTERONE; TOXICITY
- Descriptors DEC
- ANDROGENS; ANDROSTANES; ANIMALS; BIOLOGICAL MATERIALS; BLOOD; BLOOD CELLS; BLOOD PLASMA; BODY FLUIDS; HORMONES; HYDROXY COMPOUNDS; KETONES; MAMMALS; MATERIALS; ORGANIC COMPOUNDS; PESTICIDES; RODENTS; STEROID HORMONES; STEROIDS; VERTEBRATES